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Patofysiologiske mekanismer bag øjensymptomer ved primaere tumorer i corpus pineale.

Publikation: ForskningReview

Harvard

Illum, NO, Møller, M & Garde, E 1993, 'Patofysiologiske mekanismer bag øjensymptomer ved primaere tumorer i corpus pineale.' Ugeskr Laeger, vol 155, nr. 4, s. 212-215.

APA

Illum, N. O., Møller, M., & Garde, E. (1993). Patofysiologiske mekanismer bag øjensymptomer ved primaere tumorer i corpus pineale.Ugeskr Laeger, 155(4), 212-215.

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MLA

Vancouver

Author

Illum, N O; Møller, M; Garde, E / Patofysiologiske mekanismer bag øjensymptomer ved primaere tumorer i corpus pineale..

I: Ugeskr Laeger, Vol. 155, Nr. 4, 1993, s. 212-215.

Publikation: ForskningReview

Bibtex

@article{3ca47ceb017b470c8d2360e9d6e99ca3,
title = "Patofysiologiske mekanismer bag øjensymptomer ved primaere tumorer i corpus pineale.",
publisher = "Almindelige Danske Laegeforening",
author = "Illum, {N O} and M Møller and E Garde",
year = "1993",
volume = "155",
number = "4",
pages = "212--215",
journal = "Ugeskr Laeger",
issn = "0041-5782",

}

RIS

TY - JOUR

T1 - Patofysiologiske mekanismer bag øjensymptomer ved primaere tumorer i corpus pineale.

A1 - Illum,N O

A1 - Møller,M

A1 - Garde,E

AU - Illum,N O

AU - Møller,M

AU - Garde,E

PB - Almindelige Danske Laegeforening

PY - 1993

Y1 - 1993

N2 - Primary tumors of the pineal body can produce dyscoordinative movements of the eye, pupillary dilatation, paralysis of adduction during convergence and nystagmus. Obstruction of the aqueduct can cause hydrocephalus, increased intracranial pressure and papilledema. Diabetes insipidus may be a presenting symptom. Pinealocytes and the photoreceptors of the eye contain several autoantigens. In man, the best known is the S-antigen. This antigen can be detected in the cerebrospinal fluid of patients with primary tumors of the pineal body. The S-antigen, and possibly other related autoantigens, can elicit an autoimmune mediated reaction causing inflammatory eye symptoms. This recently described paraneoplastic neurologic syndrome shares properties in common with other known cancer-associated ophthalmologic syndromes characterised by rapid development of eye symptoms, rapid loss of sight and by eye manifestations prior to evident appearance of symptoms related to primary tumor growth. A primary tumor of the pineal body should be considered in patients where a monosymptomatic uveoretinitis presents without associated provoking factors. Furthermore, analyses of S-antigen in the spinal fluid can be useful in the clinical diagnosis of the same primary tumors.

AB - Primary tumors of the pineal body can produce dyscoordinative movements of the eye, pupillary dilatation, paralysis of adduction during convergence and nystagmus. Obstruction of the aqueduct can cause hydrocephalus, increased intracranial pressure and papilledema. Diabetes insipidus may be a presenting symptom. Pinealocytes and the photoreceptors of the eye contain several autoantigens. In man, the best known is the S-antigen. This antigen can be detected in the cerebrospinal fluid of patients with primary tumors of the pineal body. The S-antigen, and possibly other related autoantigens, can elicit an autoimmune mediated reaction causing inflammatory eye symptoms. This recently described paraneoplastic neurologic syndrome shares properties in common with other known cancer-associated ophthalmologic syndromes characterised by rapid development of eye symptoms, rapid loss of sight and by eye manifestations prior to evident appearance of symptoms related to primary tumor growth. A primary tumor of the pineal body should be considered in patients where a monosymptomatic uveoretinitis presents without associated provoking factors. Furthermore, analyses of S-antigen in the spinal fluid can be useful in the clinical diagnosis of the same primary tumors.

UR - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8430465&query_hl=26

JO - Ugeskr Laeger

JF - Ugeskr Laeger

SN - 0041-5782

IS - 4

VL - 155

SP - 212

EP - 215

ER -

ID: 32495129